What exactly is BV?

Here’s the short answer: Normally, the vagina maintains a delicate balance of naturally occurring bacteria. Bacterial Vaginosis (BV) occurs when that balance changes.1 It can happen to anyone, and it doesn’t mean you have poor hygiene.2

If you've never heard of BV, you’re not alone—neither have many women. Yet, BV is much more common than you’d imagine.3

BV affects more than 21 million women in the U.S. each year.4

Genetics, smoking, douching, and certain types of sexual activity are a few of the many things that can affect your vagina’s natural balance.5

About 50% of women will see BV occur again, often in the same year.6

Symptoms of BV may include 1:

  • A fishy odor
  • A thin, milky grayish-white discharge or excessive discharge
  • An itching, burning sensation or irritation

BV can increase your risk of 1,7:

  • Sexually transmitted infections (STIs) and human immunodeficiency virus (HIV), and HIV transmission to sex partners
  • Pelvic inflammatory disease (PID), which may affect fertility
  • Or can lead to late fetal loss during pregnancy, premature birth, or low birth weight

BV can only be treated with a proper prescription from your doctor.1 With Solosec™ (secnidazole), you may be able to effectively treat BV, and avoid increasing your risk of the complications associated with leaving it untreated.1,7,8 Talk to your doctor to see if Solosec is right for you, and keep reading to learn more.

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  1. Centers for Disease Control and Prevention. Bacterial vaginosis—CDC Fact Sheet. www.cdc.gov/std/bv/BV-FS-June-2017.pdf. Accessed March 29, 2018.
  2. Bilardi JE, Walker S, Temple-Smith M, et al. The burden of bacterial vaginosis: women's experience of the physical, emotional, sexual and social impact of living with recurrent bacterial vaginosis. PLoS One. 2013 Sep 11;8(9):e74378.
  3. Broumas AG, Basara LA. Potential patient preference for 3-day treatment of bacterial vaginosis: responses to new suppository form of clindamycin. Adv Ther. 2000;17(3):159-166.
  4. Chavoustie SE, Eder SE, Koltun WD, et al. Experts explore the state of bacterial vaginosis and the unmet needs facing women and providers. Int J Gynecol Obstet. 2017;137(2):107-109.
  5. Lewis FMT, Bernstein KT, Aral SO. Vaginal microbiome and its relationship to behavior, sexual health, and sexually transmitted diseases. Obstet Gynecol. 2017;129:643-654.
  6. Wilson J. Managing recurrent bacterial vaginosis. Sex Transm Infect. 2004;80:8-11.
  7. Brotman RM. Vaginal microbiome and sexually transmitted infections: an epidemiologic perspective. J Clin Investig. 2011;121(12):4610-4617.
  8. SOLOSEC [prescribing information]. Baltimore, MD: Lupin Pharmaceuticals, Inc; 2017.


Indication and Important Safety Information


SOLOSEC™ (secnidazole) 2g oral granules is a prescription medicine used to treat bacterial vaginosis in adult women.


  • You should not use SOLOSEC if you’ve had an allergic reaction to secnidazole, other ingredients of the formulation, or other nitroimidazole derivatives.
  • Vaginal yeast infections may occur with SOLOSEC and require an antifungal treatment.
  • Long term use of SOLOSEC should be avoided as it is unclear if there is a potential risk of developing cancer while taking single-dose of SOLOSEC to treat bacterial vaginosis.
  • Before taking SOLOSEC, tell your healthcare provider about all of your medical conditions, including if you
    • Are pregnant or plan to become pregnant.
    • Are breastfeeding or plan to breastfeed. You should not breastfeed for 96 hours (4 days) after taking SOLOSEC.
  • SOLOSEC is a single-dose therapy for oral use. Use SOLOSEC by sprinkling an entire packet of SOLOSEC onto applesauce, yogurt, or pudding. The entire dose should be taken at once, and finished within 30 minutes. Avoid chewing or crunching the granules. SOLOSEC should not be taken by dissolving the granules in any liquid.
  • The most common side effects of SOLOSEC include yeast infection, headache, nausea, altered taste, vomiting, diarrhea, abdominal pain, and vaginal itching.

Call your doctor for medical advice on side effects. You are encouraged to report suspected side effects of prescription drugs to FDA at www.fda.gov/MedWatch also at 1-800-FDA-1088 or contact Lupin Pharmaceuticals, Inc. at 1-844-SOLOSEC (1-844-765-6732).

Please click here for full Prescribing Information.

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